Meta-analyses for each phenotype identified two genome-wide significant variants (Table 2): one associated with variability in wellbeing (rs2940988; P = 9.93 × 10−9), located in the intronic region of the protein-coding chromosome 4 open reading frame 19 (C4orf19) gene; and one (rs60358762; P = 5.07 × 10−9) associated with variance in anxiety symptoms in adults, located in the intergenic region of the protein-coding SLC15A1 gene on chromosome 13. The gene discussed is PGCKA1; the disease is Anxiety.