Accordingly, single-cell transcriptome analysis revealed that CD69+CD103-CD8+ tissue-resident memory (Trm) cells were enriched in the livers subjected to MASH resolution, which attracted hepatic stellate cells in a CCR5-dependent manner and resulted in HSC apoptosis, thereby promoting MASH-related liver fibrosis resolution [82]. Here, CCR5 is linked to Hepatic fibrosis.