BAG3 and familial dilated cardiomyopathy: Therefore, the cardiac phenotype in BAG3-NMD p.(Pro209Leu) patients seems to be dominated by structural cardiac disease, as is the case in BAG3-DCM.5 Nevertheless, in contrast to autosomal dominant BAG3-DCM patients, p.(Pro209Leu) patients always showed restrictive cardiomyopathy.