CD36 and malaria: We measured antibodies to AMA1 (a known marker of cumulative malaria exposure [63]) by ELISA, antibodies to VSAs on PfFCR3 iRBCs predominantly expressing the CD36 and ICAM1-binding IT4VAR16 PfEMP1 variant through a flow cytometry-based surface recognition assay (SRA, gating strategy in S6A Fig), and antibodies to 35 PfEMP1 CIDR domains representing CD36 (n = 12) and EPCR (n = 17) binding CIDR domains and n = 6 other CIDR of group A PfEMP1, through a multiplex bead array [64].