To investigate whether WT1 overexpression augments bleomycin-induced pulmonary fibrosis, control and cWT1OE mice were treated with 2 tamoxifen injections per week for 7 weeks, and 3 intratracheal instillations of bleomycin at 3-week intervals for a total of 9 weeks (Figure 7A). The gene discussed is WT1; the disease is pulmonary fibrosis.