CTHRC1 and idiopathic pulmonary fibrosis: WT1 fibroblasts expressed high levels of CTHRC1, POSTN, RUNX1, and several collagen genes, including COL1A1, COL1A2, COL3A1, COL4A5, COL6A3, COL14A1, and COL16A1 in patients with IPF compared with control individuals (Figure 2E).