PVT1 and systemic lupus erythematosus: miR-30e-5p levels rose by 2.1-fold in SLE + si-Pvt1 mice (p = 0.0049) but declined by 45% in SLE + lenti-Pvt1 mice (p = 0.0132), supporting a competitive endogenous RNA (ceRNA) interaction wherein Pvt1 sequesters miR-30e-5p to derepress downstream targets.