Yang et al. 2020a, b; Zuo et al. 2024), inhibiting apoptosis through the PI3K-Akt-mTOR and P53 pathways (Kitab and Tsukiyama-Kohara 2023b; Wang et al. 2021), and suppressing ferroptosis by enhancing glutathione synthesis in liver cancer cells (Tan et al. 2022; Yang et al. 2020a, b; Zhang et al. 2024; Zuo et al. 2024). This evidence concerns the gene TP53 and liver cancer.