To explore the key surface O‐glycosylated proteins on NE cancer cells that bind and activate MBL signaling, the cell membrane proteins of the rb1Δ/Δp53Δ/Δ Galnt9‐KD‐NEPC organoids and rb1Δ/Δp53Δ/Δ scramble counterparts were fractionated and incubated with purified recombinant His‐tagged MBL2 protein in vitro (Figure8a). This evidence concerns the gene MBL2 and cancer.