SRC and atherosclerosis: The downstream Src kinase of GPCRs is a signaling determinant of cellular senescence,[26] which also plays a complicated role in the pathogenesis of CVD.[53] Our study supports that saracatinib can mitigate atherosclerosis by inhibiting macrophage senescence rather than by reducing blood lipid levels, underscoring the role of Src‐mediated cellular senescence in atherosclerosis.