The results of immunohistochemical staining for Ki67, Stat3, p‐Stat3 and Gpx4 were consistent with the above cell experiments, indicating that FK866+C188‐9_Gel treatment inhibited Stat3/Gpx4 signaling, activated ferroptosis and decreased tumor proliferation (Figure 9G,H). This evidence concerns the gene MKI67 and neoplasm.