Functionally, CXCL13 CAR T cells demonstrated reduced expression of exhaustion markers, including PD‐1 and TIM3 (Figure 8g,h), enhanced mitochondrial health, and elevated ATP production (Figure 8i,j), which collectively contributed to their enhanced cytotoxic activity against tumor cells in vitro (Figure 8k). Here, HAVCR2 is linked to neoplasm.