DYNLL1 and osteoporosis: Previous studies have shown that natural Chinese herbal medicines and compounds, such as Curculigo orchioides Gaertn, Psoralea corylifolia (L.)Medik, and Eucommia ulmoides Oliv, can help maintain bone remodeling homeostasis and mitigate the progression of osteoporosis.[27] In our study, we identified a specific mechanism through which PIN alleviates osteoclast activation, and we also demonstrated its therapeutic potential in promoting osteogenic differentiation and mineralization.