To explore the function of CATED in HGSOC platinum resistance, we established stable cell lines with CATED overexpression and knockdown in SKOV3 and COV504 cells (Figure S3a, Supporting Information), which are two cell lines commonly used in ovarian cancer research.[15, 16] Increased cell viability was observed in the CCK8 assay upon CATED overexpression, whereas CATED knockdown decreased cell viability (Figure2a,b). The gene discussed is ZNF404; the disease is ovarian cancer.