ZNF404 and neoplasm: To explore the roles of sEV‐transmitted lncRNAs in HGSOC platinum‐resistance, we utilized RNA‐seq for differential expression of lncRNAs in HGSOC platinum‐resistant and platinum‐sensitive HGSOC patient's tumor‐derived sEVs and identified a novel lncRNA, CATED (Cisplatin‐Associated Tumor small Extracellular Vesicle‐Derived LncRNA, ENSG00000267058) upregulated in tumor‐derived sEVs from patients with platinum‐resistant HGSOC.