GLO1 and neoplasm: Furthermore, given that metastasis is a multifaceted process encompassing various stages, including in situ tumor growth, angiogenesis, EMT, invasion, infiltration, circulation survival, extravasation, dormancy, metastatic tumor growth, and interaction with TME components, it is necessary to elucidate the intricate mechanisms by which GLO1 influences the progression of LN metastasis in breast cancer.[77]