Based on the node connectivity within the PPI network (Figure 1D), 10 core genes regulating biliary atresia were identified: MFAP4, FBLN5, DPT, PRELP, CEACAM6, OMD, APSN, OGN, CEACAM8, and FBLN1. The gene discussed is FBLN1; the disease is biliary atresia.