Genomic studies have identified driver mutations associated with primary lung cancer, including epidermal growth factor receptor (EGFR) [11, 12], anaplastic lymphoma kinase (ALK) [13], ROS1 Proto-Oncogene Tyrosine Kinase Receptor (ROS1) [14] and Serine/Threonine-Protein Kinase BRAF (BRAF) [15]. The gene discussed is ROS1; the disease is lung cancer.