MMP9 and hypertensive disorder: For example, patients treated with lisinopril or candesartan exhibited significant reductions in both BP and MMP-9 concentrations after 3 months of treatment, suggesting a potential for MMP inhibitors to serve dual purposes in managing hypertension and reducing organ damage (Chuliá-Peris et al., 2022; Broekaart et al., 2021; Laronha et al., 2020).