While all the fusion proteins we have discussed so far have YAP or TAZ as the N-terminal fusion partner, the ZFTA fusion subset of supratentorial ependymomas includes rare cases containing ZFTA::YAP1 gene fusions, in which the entire coding frame of YAP as a C-terminal attachment is fused to the zinc fingers of ZFTA (Kupp et al. 2021, Parker et al. 2014). The gene discussed is YAP1; the disease is ependymoma.