NUTM1 and head and neck carcinoma: Sekine et al. (2019), studying poroma and porocarcinoma, later demonstrated a similar phenotype, showing that the fusion proteins YAP::MAML2, YAP::NUTM1, and TAZ::NUTM1 each had the capacity to transform 3T3 cells and immortalized human dermal keratinocytes (Sekine et al. 2019). Of note, the cell lines AM-38 (glioblastoma), ES-2 (ovarian carcinoma), and SAS (head and neck carcinoma) were identified to have YAP1::MAML2 gene fusions that were required for cell fitness (Picco et al. 2019).