Points for each five predictors ranges from 0 to 100 where each corresponding predictors; BMI and HbA1c within 0–10, ALP and Ca19-9 within 0–20 and CEA from 0 to 100 if added together to give their respective total points which total from 0 to 130 for their corresponding risk of pancreatic cancer to be associated with risk scoring from −50 to 450 are to be predicted linearly for reflecting risk of pancreatic cancer from 0.5 to 1 in proportion on the basis as shown in Figure 6. The gene discussed is CEACAM5; the disease is familial pancreatic carcinoma.