In the training set, various variables were significantly different between case and control groups, including Gender, Age, Smoking, Drinking, SBP, Hypertension, Diabetes, Dyslipidemia, PLT, NLR, FBG, GA, P, ALB, GGT, Crea, Urea, APTT, Neut, PLT- PCT, LDH, FDP, D-Dimer, ESR, C1q, Lymph, RDW-CV, PDW, IgA, WBC, α-HBDH, apoE, DBIL, Mono, C4, TP, UA, MHR, and TyG(P < 0.05), as displayed in S1 Table. The gene discussed is APOE; the disease is diabetes mellitus.