In the training set, various variables were significantly different between case and control groups, including Gender, Age, Smoking, Drinking, SBP, Hypertension, Diabetes, Dyslipidemia, PLT, NLR, FBG, GA, P, ALB, GGT, Crea, Urea, APTT, Neut, PLT- PCT, LDH, FDP, D-Dimer, ESR, C1q, Lymph, RDW-CV, PDW, IgA, WBC, α-HBDH, apoE, DBIL, Mono, C4, TP, UA, MHR, and TyG(P < 0.05), as displayed in S1 Table. This evidence concerns the gene APOE and hypertensive disorder.