PSMB7 and parasitic infectious disease: In the protozoan Acanthamoeba castellanii, the EV-associated proteasome regulates encystation and extracellular proteolytic activities (Lin et al., 2019), whereas in Trichinella spiralis, the EV-associated proteasome subunit beta type-7 (PST) is expressed at different developmental stages and confers protective immunity against parasite infection in BALB/c mice immunized with the recombinant PST (Yang et al., 2015; Gao et al., 2022).