While Junb, Serpine1, and Slc2a4 have been previously reported to be associated with anthracycline‐induced cardiotoxicity,[33, 34, 35] subsequent validation in our DOX‐induced cardiomyopathy (DoIC) mouse model revealed EBBP as the most significantly altered gene among the remaining candidates (Ebbp, Mphosph10, Slc43a2, Il4ra, Rai14, Msn, Csf3r, Fpr1, Adamts7, Mrgprh, Pm20d1) (Figure 1B). Here, IL4R is linked to cardiomyopathy.