RUNX1 and acute lymphoblastic leukemia: Similarly, for maternal alcohol‐associated methylation, where constitutive methylation across subtypes was observed to significantly overlap, for specific subtypes, this relationship was only observed for T‐ALL (p = 0.005), ETV6::RUNX1 (p = 0.028) and undefined leukaemias (p = 0.040), with only T‐ALL (p = 0.008) and ETV6::RUNX1 (p = 0.045) subtypes having significantly concordant directional methylation changes overlapping (Table 3).