Furthermore, curcumin augments the effectiveness of Doxorubicin and Paclitaxel in overcoming MDR in lung cancer (A549), ovarian cancer (SK-OV-3), and colon cancer (HCT-8) cells by inhibiting both the protein function and expression of P-gp [307, 308]. The gene discussed is PGP; the disease is malignant colon neoplasm.