Curcumin triggers cell apoptosis in lung, colon, liver, cervical, and pancreatic cancers by up-regulating pro-apoptotic protein expression (Bax and Bad) or by inhibiting anti-apoptotic proteins (Bcl-xL and Bcl-2), as well as activating Caspase pathway [340, 356–359]. This evidence concerns the gene BCL2 and familial pancreatic carcinoma.