Moreover, curcumin down-regulates the protein expression of GPX4 and Solute carrier family 7 member 11 (SLC7A11) to induce ferroptosis in colon cancer (HCT-8) and follicular thyroid cancer (FTC-133 and FTC-238) cells [332, 333]. The gene discussed is SLC7A11; the disease is malignant colon neoplasm.