Besides, another study published in Chinese Medicine explored the effects of Cucurbitacin B on inhibiting transforming growth factor-beta 1 (TGF-β1)-induced epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC), revealing that Cucurbitacin B modulates ROS production and the phosphoinositide 3-kinase (PI3K)/AKT/ mammalian target of rapamycin (mTOR) signaling pathways [17]. Here, TGFB1 is linked to non-small cell lung carcinoma.