Resveratrol activates Caspase-3 and Caspase-8, and up-regulates the protein expression of Bax [851–853], while inhibiting anti-apoptotic proteins like Bcl-2 [854], in order to induce apoptosis in luminal squamous cell carcinoma, cervical carcinoma, colon carcinoma, ovarian carcinoma, and uterine leiomyoma cells. The gene discussed is CASP3; the disease is squamous cell carcinoma.