GSK3B and preeclampsia: In RNA-seq, we did not detect significant changes in the mRNA expression of β-catenin (CTNNB1 [catenin β1]) or glycogen synthase kinase 3 beta (GSK3β), two critical downstream effectors of the canonical Wnt pathway [126, 129], suggesting that the noncanonical Wnt pathway may play an important role in platelet function during preeclampsia.