These findings are consistent with our analysis of human-derived cell lines (Figs. 1B and  EV1C–E; Appendix Fig. S1B), suggesting that CMA is regulated by NCoR1/RARα in human NSCLC tumors and, therefore, disrupting the NCoR1/RARα interaction to inhibit CMA may have translational value in NSCLC tumors. The gene discussed is RARA; the disease is non-small cell lung carcinoma.