However, because 12/15-LOX oxylipins were significantly increased in the colon of helminth-infected mice fed a low ω-6 diet, which were not prone to increased tumor development, our data suggest that tumor burden was not solely linked to increased expression of Alox15, or the basal level of the 12/15-LOX-derived oxylipins following Hpb infection. This evidence concerns the gene ALOX15 and neoplasm.