BRCA1 and breast cancer: The remaining percentage is related to inherited genes like Breast Cancer gene 1 and Breast Cancer gene 2 (BRCA1/BRCA2).[6] Increasing age, positive family history, reproductive factors such as early menarche, late menopause, late age at first pregnancy, and low parity, both endogenous and exogenous estrogen in the form of oral contraceptives and hormone replacement therapy and sedentary lifestyle are important risk factors of breast cancer.[7] Screening plays a significant role in the prevention and early detection of breast cancer, with up to a 20% reduction in mortality.