FCGR2A and infection: Based on the trend of keywords evolution, the most recent hotspot is “COVID-19” and “SARS-CoV-2,” by article review, it suggested that FcγR involved in the development and treatment of a wide range of infections, and although activation of Fc-FcγR has been shown to inhibit the development of infections, if inappropriately over-activated, it will promote the development of viral infections.[29]