Blood markers, including amylase, cholesterol, and C-reactive protein (CRP),[12] are recognized as possible signs of pancreatitis, and observational studies indicate a connection between pancreatitis and metabolic conditions, such as overweight[13,14] and type 2 Diabetes Mellitus (T2DM).[15,16] Although observational research can handle acknowledged confounding factors using statistical methods, the presence of unknown or undocumented confounding factors may still impact the results. The gene discussed is CRP; the disease is type 2 diabetes mellitus.