The obtained results demonstrated that the AF/P ratio was significantly elevated in the study group compared to the control group for SOD (P = .027), TAC (P < .001), TOC (P < .0001), and adiponectin (P = .002), whereas a significant decrease was observed for SIRT1 (P = .036) (Fig. 4). This evidence concerns the gene SIRT1 and atrial fibrillation.