Moderate correlations (R > 0.6, p < 10-8) between the inflammation marker (Ψj) and peak IFN concentrations were found in both the immunosuppressed and COVID-19 reference VPCs (Fig 4E-4F), with severe immunosuppressed patients (Ψj > 4) having IFN peak delays more often than patients from other VPCs. The gene discussed is IFNA1; the disease is COVID-19.