Similar effects were also observed in A549 adenocarcinoma human alveolar basal epithelial cells cultured on FN‐grafted titanium discs or discs grafted with the cell attachment site (CAS) fragment from FN, but not laminin‐ (LAM, responsible for binding to integrins α1β1, α2β1, α3β1, α6β1, α7β1, and α6β4 without involving RGD) and vitronectin‐grafted (VTN; responsible for αvβ3 integrin binding) titanium discs (Figure S7A,B, Supporting Information). The gene discussed is FN1; the disease is adenocarcinoma.