Moreover, high prevalence of amoebiasis, caused by Entamoeba histolytica infection, has been recorded among Orang Asli (Anuar et al. 2012), and in a study on Bangladeshi children, it has been found that the heterozygous haplotype DQB1*06:01–DRB1*15:01 had protective effects against this infection (Duggal et al. 2004). Here, HLA-DRB1 is linked to infection.