To assess changes in the relative expressions of the GPR78 and CotH3 genes, this study used the real-time quantitative PCR method to quantify their target miRNAs in macrophages derived from human monocytes (monocyte-derived macrophages [MDMs]), mice models, and sinus tissue from diabetic patients with mucormycosis. This evidence concerns the gene GPR78 and Zygomycosis.