The KEGG enrichment analysis revealed that these targets were significantly associated with 120 signaling pathways (p < 0.05), including the PI3K–Akt signaling pathway, Alzheimer's disease, pathways of neurodegeneration across multiple diseases, and neuroactive ligand–receptor interactions, among others (Figure 7). This evidence concerns the gene AKT1 and early-onset autosomal dominant Alzheimer disease.