Therefore, we utilized an alternative single‐cell dataset (GSE136861) that allowed for the detection of IL6‐AS1 expression [33] after quality filtering (25 samples: 13 controls/12 COPD). Unsupervised clustering identified 22 cell subtypes (Figures 4B and S13A,B), with IL6‐AS1 predominantly expressed in macrophages (Macrophages_2 cluster), fibroblasts, and endothelial cells, but absent in alveolar epithelium (Figure S13D and Table S4). The gene discussed is IL6; the disease is chronic obstructive pulmonary disease.