CDH17 and colorectal carcinoma: To ascertain the suitability of CDH17 for CAR-NK therapy targeting PDAC, GC, and CRC, we first performed single-cell RNA-seq (scRNA-seq) data analysis using three different datasets (GSE156405, GSE163558, and GSE188711) and annotated all cells based on the original studies (Fig. 1A–C, and E).