ST3GAL1 and infection: Enhanced HU02Av−H5 infection of HEKΔSiaN cells upon transfection by ST3Gal1 (15% of WT) or ST3Gal2 (30% of WT) was unexpectedly observed (Figure 3A-c) which suggests that ST3Gal1 and 2 may indeed use type II LN substrates on N-glycans.