PPARA and fatty liver disease: Geniposide promotes lipolysis and fatty acid β-oxidation, promotes lipoprotein lipase (LPL) and apolipoprotein A (Apo A) expression, and reduces fatty acid synthetase expression by upregulating PPARα and CPT-1α gene expression in hepatic tissues, which reduces cholesterol and TG production and ameliorates hepatic steatosis (Guan et al., 2018).