CD4 and neoplasm: WGCNA revealed eight gene modules of high co-expression with 22 immune cells, among which the MEturquoise module had the strongest correlation with tumor-infiltrated immune cells, and the genes were closely related with macrophages M1 (p < 0.001), CD8+ T cells (p < 0.001), gamma delta T cells (p < 0.001), and memory activated CD4+ T cells (p < 0.001; Figure 1C; Supplementary Figures S1E, F).