RIPK1 and malignant colon neoplasm: Another investigation found that the tributyltin ferulate derivative of FA was tested on HCT116, HT-29, and Caco-2 colon cancer cells at a concentration of 40 μM which stopped the G0/G1 phase of the cell cycle, leading to a reduction in RIPK1 and an elevating in cytotoxicity, ultimately causing the death of the cells [120].