E2F4 and Familial prostate cancer: Eroğlu et al. show that FA plays a crucial role in the case of reducing the invasion of prostate cancer (PC-3) in vitro at a concentration of 20 μM–2 mM by increasing expressions of ATR, ATM, CDKN1A, CDKN1B, E2F4, RB1, and TP53 and reducing the gene expressions of CCND1, CCND2, CCND3, CDK2, CDK4, and CDK6 level in PC-3 cells [32].