Moreover, venous thrombosis is a common and severe complication in cancer patients, often driven by tumor-derived prothrombogenic extracellular vesicles (EVs).85, 86, 87Recent evidence, including data from Osorio et al.,88highlights the presence of HSP47 on the surface of small EVs isolated from human blood. The gene discussed is SERPINH1; the disease is Venous thrombosis.