A study published in the “Journal of Thrombosis and Haemostasis” by Sasikumar highlights HSP47 as a platelet collagen-binding protein that contributes to thrombosis and hemostasis.13The study notes an increase in bleeding time associated with HSP47 activity, although there are currently no direct data available regarding its role in human cancer-related bleeding. This evidence concerns the gene SERPINH1 and cancer.