Similarly, in rectal cancer, significant correlations were observed with CD3E, HAVCR2, IL10, CD1C, CEACAM8, CCR7, STAT3, CTLA4, ITGAM, HLA-DPB1, FOXP3, CCL2, KIR3DL1, and STAT1 (P < 0.001; Cor value ≥ 0.40). The gene discussed is CTLA4; the disease is rectal cancer.