Furthermore, NMB demonstrated involvement in multiple KEGG pathways, including JAK-STAT signaling (29, 30), MAPK signaling pathway (31, 32), Alzheimers disease, Amyotrophic lateral sclerosis als, Antigen processing and presentation, Arginine-and-proline-metabolism, Aminoacyl trna biosynthesis, Aminoacyl trna biosynthesis. Here, MT-TA is linked to early-onset autosomal dominant Alzheimer disease.