For instance, a c-Met binding peptide with high affinity for c-Met overexpressed in triple-negative breast cancer, and a tumor-targeting peptide, cyclic RGD peptide (cRGD), binding to integrin αvβ3 receptor on diffuse intrinsic pontine glioma (DIPG) cells, were immobilized on the surface of EV-coated nanoplatforms (82, 83). This evidence concerns the gene MET and diffuse intrinsic pontine glioma.