Key genes such as CYFIP1, DCP2, EIF4E, EIF4E2, EIF4G3, LARP1, LSM1, METTL1, NCBP1, NCBP2, NUDT3, NUDT11, and WDR4 were found to be significant predictors of overall survival in HCC patients (Figure S3). This evidence concerns the gene NUDT3 and hepatocellular carcinoma.