APP and inclusion body myositis: Muscle biopsies of IBM patients typically show concomitant chronic inflammatory changes, with endomysial infiltration of immune cells and MHC‐I upregulation, degenerative features with cytoplasmic deposits of aggregated/misfolded hallmark proteins (SQSTM1/p62, amyloid precursor protein [APP] and TDP43) and mitochondrial abnormalities [1].