Moreover, 13 genes were upregulated in PBMCs of all CRC patients’ groups; CCR3 (fold regulation 59.21), CD2 (fold regulation 3.07), CD27 (fold regulation 6.39), CD3G (fold regulation 4.15), CD8B (fold regulation 3.25), FAS (fold regulation 3.94), IL10 (fold regulation 39), IL18R1 (fold regulation 82.39), IL5 (fold regulation 20.4), LAG3 (fold regulation 19.88), MAP3K7 (fold regulation 4.07), TLR1 (fold regulation 6.45), and TLR6 (fold regulation 18.87). The gene discussed is IL18R1; the disease is colorectal carcinoma.