Furthermore, we performed GSVA analysis of KEGG signaling pathway to gain more insights into the functional divergence of γδ T cells: The status of DLBCL disease upregulates a list of genes in γδ T cells categorized into signaling pathways, including cell apoptosis, TGF-β signaling pathway (Fig. 2B). The gene discussed is TGFB1; the disease is diffuse large B-cell lymphoma.