PRKCA participates in processes intricately linked to tumor-promoting events [47], and in PC-3 and DU-145 cell lines exhibits upregulation [48], whereas, in LNCaP cells, the apoptotic response induced by Phorbol 12-myristate 13-acetate (PMA) is promoted by NF-kB and active PRKCA mutants [49]. Here, PRKCA is linked to neoplasm.